web.config for specific groups/filters

We have some cases when we connect, clients don't want the screen to be locked when exiting or hiding the connection bar, what ever the case may be.

Would it be possible to apply a different web.config to different client groups/filters? I know the app.config can be modified but will be reset if updated but there is no way to do this for the web.config. It would be great to have both the web.config and app.config settings be configurable for certain groups rather than just global.